Active Vitamin B12 is often referred to as holotranscobalamin (holoTC) or active B12. It is the physiologically active component of vitamin B12 that your body’s cells can easily absorb and use.
Is it for me?
The active vitamin B12 blood test, which assesses holoTC levels, is frequently used to more accurately detect vitamin B12 deficiency than the total B12 measurement. A vitamin B12 deficiency can cause pernicious anaemia, which is characterised by a decrease in the number of red blood cells as well as a variety of neurological symptoms such as numbness, tingling, and cognitive difficulties.
This test is especially useful when there are clinical concerns of vitamin B12 insufficiency, even though total B12 levels are within normal limits. It gives a more detailed assessment of the bioavailable vitamin B12 that your body can utilise.